A teenager suffered multiple stab wounds during an incident early Saturday morning at the On the Run gas station in Red Bay, police say.
The RCIP is appealing for witnesses to come forward.
Police were alerted to the incident at around 4.30am when the 17-year-old arrived at the Cayman Islands Hospital. He had been attacked at the gas station sometime earlier, police said.
The teenager has been flown to the US for treatment and is in serious condition, police said.
Anyone with information should call DC Colin Ormule on 949-4222 or Crime Stoppers on 800 TIPS. Callers to Crime Stoppers could receive a cash award should their information lead to an arrest.