One of the drivers, a 50-year-old male, remains under observation at Cayman Islands Hospital in George Town, police said. His injuries are considered to be serious, but not critical, according to a news release issued by the Royal Cayman Islands Police Service.
The other driver, a 49-year-old woman, has been treated and released, authorities said.
The accident occurred about 7.15pm in the vicinity of the Bodden Town Post Office, police said. Traffic through the district was briefly diverted Sunday night via Anton Bodden Drive.
No further information was immediately available.