A man suffered serious head and neck injuries after being attacked with a machete in the vicinity of the Dream Night Club on West Bay Road.
Two other men were injured in a separate incident in George Town following an “after hours session” on Shedden Road.
Detectives are appealing for witnesses to both attacks, which occurred in the early hours on Saturday.
Detective Chief Inspector Malcolm Kay said, “This weekend, we have once again seen two very violent incidents involving young men using knives and machetes to inflict very serious injuries to their victims.
“These incidents of violence will be thoroughly investigated and the offenders will be sought out and prosecuted to the fullest extent of the law.”
He added, “While we continuously strive to investigate these incidents, I would also like to encourage anyone who witnessed them or has any information about these horrific attacks to come forward in confidence and assist us with our inquiries.”
The machete attack took place just after 3 a.m. Saturday. Police received reports that two males with machetes were chasing another male along West Bay Road near the nightclub.
Armed police officers were sent to the scene but “all parties had departed the area,” according to a police statement. The injured male was later treated for head and neck injuries at the Cayman Islands Hospital and has since been discharged.
Police had earlier attended reports of a brawl on Shedden Road at around 2:30 a.m. in the aftermath of a late night “session.”
One man received a cut to the face, while another man suffered a swollen eye and a wound to the face.
Anyone with information about either incident can call George Town CID at 949-4222 or call Crimestoppers anonymously on 800-8477(TIPS).