Police and ambulance crews were called to the scene of a two-vehicle collision in Stake Bay at 11:23 p.m.
The teen was taken to Faith Hospital on the Brac for treatment, but he died from his injuries.
Police have not officially released the name of the victim in Friday’s night’s accident. Officers from Grand Cayman will be traveling to the Brac to assist with the investigation.
The incident comes just a week after 49-year-old Jose Abel Zelaya was killed in another car accident on the Brac.