Royal Cayman Islands Police responded to break up a fight involving more than two dozen people outside an East End bar early Saturday.
Officers were also looking into reports that gunshots had been fired at some point during the struggle.
No serious injuries were reported, although officers said that several participants in the fight suffered cuts and bruises.
Five people were taken into custody for questioning in relation to the fight.
Police said the fight broke out among about 30 people just after 1.30am Saturday. They did not say if the dispute was believed to be gang-related.